How to value creatinine renal function is the reaction?

How to value creatinine renal function is the reaction?

Different reaction creatinine values ​​different stages of renal disease progression:

a. decompensated renal insufficiency, serum creatinine (Scr) 133 ~ 177umol / L, due to large renal compensatory ability, and therefore clinical renal function despite the decline, but its excretion of metabolites and regulate water and electrolyte balance remains can meet the normal needs, not on clinical symptoms and renal function tests are normal range or occasionally slightly higher phenomenon.

b. renal insufficiency decompensated (also known as renal insufficiency, azotemia), serum creatinine (Scr) 177 ~ 442umol / L, an increase in the number of glomerular sclerosis fibrosis, approximately 60% -75% damage, renal excretion of metabolic waste has a certain obstacles, serum creatinine or blood urea nitrogen higher than normal. Patients with anemia, fatigue, weakness, weight loss, mental focus and other difficult, but often overlooked. If dehydration, infection, bleeding and other conditions, will accelerate the progress of the disease.

. c renal failure, serum creatinine (Scr) 442-707umol / L, glomerulosclerosis, tubular - interstitial fibrosis, renal vascular fibrosis, lead to serious kidney dysfunction, significant anemia, nocturia, blood creatinine, blood urea nitrogen increased significantly, and often acidosis, as this period without formal treatment system, the development of end-stage renal disease, treatment is more difficult.

d. uremia or end-stage renal insufficiency, serum creatinine (Scr)> 707umoll / L. Uremia patients with renal insufficiency glomerular injury is more than 95%, there are severe clinical symptoms such as severe nausea, vomiting, oliguria, edema, malignant hypertension, severe anemia, pruritus, mouth urine smell of urine and the like.

Thus when the creatinine over 133 when you need timely treatment, otherwise has been increasing along with kidney damage, the consequences could be disastrous.

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